Description
Convert BAM files to cooler format for Hi-C analysis
Input
Name
Description
Pattern
The input channel containing a list of BAM files Structure: [ val(meta), [path(bam1), path(bam2), ...] ]
*.bam The input channel containing chromosome sizes file Structure: [ val(meta), path(chrom_sizes) ]
*.{txt,sizes} Output
Name
Description
Pattern
Channel containing merged cooler file Structure: [ val(meta), path(cool) ]
*.cool Components
-
bedtools/bamtobedsort
sanger-tol/nf-core-modules -
contactbed
sanger-tol/nf-core-modules -
generatecontactsindex
sanger-tol/nf-core-modules -
hic/getpairedcontactbed
sanger-tol/nf-core-modules -
cooler/cload
nf-core/modules -
cooler/merge
nf-core/modules -
cooler/zoomify
nf-core/modules